Calcium glycerophosphate is a phosphorus and calcium
dietary supplement which acts as a base when added to food or drink, bringing the acid down to a neutral level.
It is known to reduce cellular inflammation in the urinary bladder. It is known as an acid-blocker.
Calcium glycerophosphate is a specially processed solution containing calcium glycerophosphate and calcium lactate.
Calcium glycerophosphate is isotonic, with a pH of about 7 or somewhat above. (Other calcium solutions are usually quite acid,
with pH values of 4.5 to 5.5). Each 10 ml Calphosan contains calcium glycerophosphate 50 mg and calcium lactate 50 mg in a
physiological solution of sodium chloride, with 0.25% phenol as a preservative.
Calcium Glycerophosphate, Oral may interact with the following
These medications may interact and cause very harmful effects. Consult your healthcare
professional (e.g., doctor or pharmacist) for more information. DI-TRIVALENT CATIONS/TETRACYCLINES
These medications may cause some risk when taken together. Consult your healthcare
professional (e.g., doctor or pharmacist) for more information.
SELECTED MINERALS/ORAL IRON SUPPLEMENTS
DI-; TRIVALENT CATIONS/CHLOROQUINE; HYDROXYCHLOROQUINE
ORAL CALCIUM PRODUCTS/ESTRAMUSTINE
ORAL CALCIUM PRODUCTS/STRONTIUM
ORAL CALCIUM PRODUCTS/SELECTED ORAL QUINOLONES
CALCIUM SUPPLEMENTS/CALCIUM CHANNEL BLOCKERS
Glycerophosphate: first step in the phosphatidic acid synthesis pathway; Any salt or ester of glycerophosphoric
terms for Glycerophosphate:
Phosphatidic Acids glycerophosphorylcholine============================================
Prelief Dietary Supplement Acid Relief 300 Tablets
:Product Code 652255: Sale Price $21.60 AkPharma
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Prelief is calcium glycerophosphate, a food-grade mineral classified
as a dietary supplement, for use with acidic foods and beverages for more comfortable eating. Suggested Use: Just take 2 tablets
3 times a day; best with meals. Also 2 tablets at bedtime if desired. You can use more tablets as needed. Ingredients: Supplement
Facts Serving Size: 2 Tablets (680 mg) Servings Per Container: 150 Amount per Serving % Daily Value Calcium (per tablet) 130
mg 13% Phosphorus (per tablet) 100 mg 10% * Daily Value not established. Ingredients: Calcium Glycerophosphate, Magnesium
Drug Interaction Precautions: Calcium may interfere with efficacy of some medications. If a medication
is being taken, check with physician, pharmacist or other health professional about the possible interactions of calcium with
that medication. No other drug interactions known.
Warnings: People who have been advised by their physician
not to take calcium, phosphorous or glycerin/glycerol should consult with their physician before using Prelief.
Tablets and Powder (AK Pharma) PRODUCT OVERVIEW
Prelief is AkPharma's brand name for calcium glycerophosphate which has a number of important uses. These fields include:
Urinary : As a palliative in interstitial
cystitis, prostatitis, overactive
Intestinal : As a symptoms reducer in irritable
Prelief is taken in periodic dosages, regardless
of meals or foods eaten. Clinical studies demonstrate that such use greatly reduces urinary pain and urgency in overactive
bladder. Prelief is also used beneficially in terms of pain and urgency with interstitial cystitis and prostatitis.
A pilot clinical study suggests beneficial use by persons with
diarrhea-predominant irritable bowel syndrome (IBS) and a clinical study to confirm this is nearing completion. Clinical studies
are also underway to confirm cellular effects in interstitial cystitis.
Safety Information: Prelief is made from an FDA Generally Recognized as Safe (GRAS) 1 mineral and is also listed in the Food Chemicals Codex (FCC). 2
PRODUCT INFORMATION Description:
Prelief Tablets : Each tablet contains
345 mg calcium glycerophosphate (65 mg of elemental calcium). The tablets also contain 0.25% magnesium stearate as a processing aid. Two tablets are equivalent to 690 mg calcium glycerophosphate (130mg of elemental calcium).
Prelief Powder : Each ¼ teaspoon usage of powder is comparable to two tablets. The powder dissolves rapidly in
food or non-alcoholic beverages. Tablets are recommended for taking with alcoholic beverages.
Two tablets or about ¼ teaspoon of powder provides 15% (130 mg)
of the FDA Recommended Daily Intake (RDI) for calcium and 10% (100 mg) of the FDA RDI for phosphorus. No sodium; no aluminum;
no sugar; no potassium.
Reasons for Use:
Prelief is used as an intervention in certain identifiable urinary and intestinal problems such as interstitial
cystitis, prostatitis, overactive bladder and irritable bowel syndrome.
a mechanism not fully elucidated, Prelief appears to reduce cellular inflammation in the urinary bladder. It also appears
to non-irritatively encourage cellular reproduction. This is possibly a result of Prelief's uniquely free calcium ion
and/or the glycerophosphate moiety, working singly or together. In addition, Prelief neutralizes the acid found in a large
number of foods which many people find cause them discomfort.
Tablets: 2-3 tablets, 2 times a day.
Powder: ¼ teaspoon of powder 2 times a day. More can be used when needed.
is Kosher and Parve.
Tablets: 60, 120 and 300-tablet bottles.
Powder: Portable 20-use (correspondent to 40 tablets) squeeze bottle and 150-serving shaker.
None, except as may apply below.
NOTE: These photos can be used only for identification by shape, color, and imprint.
They do not depict actual or relative size.
The product samples shown here have been supplied by the
manufacturer and reproduced in full color by PDR as a quick-reference identification aid. While every effort has been made
to assure accurate reproduction, please remember that any visual identification should be considered preliminary. In cases
of poisoning or suspected overdosage, the drug's identity should be verified by chemical analysis.
Adverse Reactions: None known.
Interactions with Drugs: Calcium may interfere with the availability of some antibiotics. Check with drug publications.
None, except for people who have been advised by their physician not to take calcium, phosphorus or glycerin/glycerol.
1 21 CFR §184.1201
2 Food Chemicals Codex, 4th Edition, pp 60-61
For more information, please write or call toll-free 1-800-994-4711.
P.O. Box 111
2004-2005© AkPharma Inc. All rights reserved.
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Glycerol 3-phosphate is an organophosphate derived from phosphoric acid and glycerol. It is a component of glycerophospholipids. It should not be confused with the similarly named glycerate 3-phosphate or glyceraldehyde 3-phosphate. The L-configuration is the active enantiomer.
Glycerol 3-phosphate is produced from glycerol, the triose sugar backbone of triglycerides and glycerophospholipids, by the enzyme glycerol kinase. Glycerol 3-phosphate may then be converted by dehydrogenation to dihydroxyacetone phosphate (DHAP) by the enzyme glycerol-3-phosphate dehydrogenase. DHAP can then be rearranged into glyceraldehyde 3-phosphate(GA3P) by triose phosphate isomerase(TIM), and feed into glycolysis.
The glycerol 3-phosphate shuttle is used to rapidly regenerate NAD+ in brain and skeletal muscle cells of mammals.
 See also
Potassium glycerophosphate Dipotassium 2,3-dihydroxypropyl
The molecular formula of Potassium glycerophosphate (CAS NO.1319-69-3) is C3H7K2O6P.
The molecular weight of Potassium glycerophosphate (CAS NO.1319-69-3) is 248.25.
Synonyms of Potassium
Uses Potassium glycerophosphate (CAS
NO.1319-69-3) is used as nutritional supplements.
from the glycerol phosphate mixed with phosphorus pentoxide or partial,then heating and refining with potassium carbonate,in
the end,concentrating by heating.
Safety Profile: Poison by intravenous route. Moderately toxic by intraperitoneal route. When heated to decomposition it emits acrid
smoke and irritating fumes.Safety information of Potassium glycerophosphate